Overview
Human Erythropoietin Injection (EPO) is a recombinant protein therapy designed to stimulate the production of red blood cells (RBCs) in the bone marrow. It is commonly prescribed to treat anemia associated with chronic kidney disease, chemotherapy, or certain medical conditions where natural erythropoietin levels are insufficient.
Active Ingredient
Recombinant Human Erythropoietin (rHuEPO)
Strength: 3000 IU per vial
Mechanism of Action
Erythropoietin is a glycoprotein hormone naturally produced by the kidneys. This synthetic version mimics its biological function, binding to erythroid progenitor cells in the bone marrow and promoting their survival, proliferation, and differentiation into mature red blood cells.
Indications
Anemia due to chronic renal failure (dialysis or pre-dialysis patients)
Anemia induced by chemotherapy in cancer patients
Anemia in patients with HIV treated with zidovudine
Pre- and post-surgical use in specific cases to reduce the need for blood transfusions
Benefits
Increases hemoglobin and hematocrit levels
Reduces symptoms of anemia (fatigue, weakness, shortness of breath)
Improves quality of life and exercise tolerance
Decreases dependence on blood transfusions
Dosage Form
Sterile injection, 3000 IU per vial/syringe (subcutaneous or intravenous administration depending on clinical need)
Manufacturer
Harbin Pharmaceutical Group (HPGC) – Biotech Division
Storage
Store refrigerated at 2–8°C.
Do not freeze.
Protect from light.
Important Notes
Use only under medical supervision.
Dosage and treatment duration vary according to patient’s hemoglobin levels and clinical condition.
Regular monitoring of hemoglobin and blood pressure is necessary.
Potential side effects: hypertension, flu-like symptoms, headache, joint pain, or increased risk of thrombotic events.
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